Yoshihide Fujiyama Selected Research

Dextran Sulfate

1/2013	Neutralization of complement component C5 ameliorates the development of dextran sulfate sodium (DSS)-colitis in mice.
11/2012	Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis.
10/2011	Interleukin-33 suppresses Notch ligand expression and prevents goblet cell depletion in dextran sulfate sodium-induced colitis.
10/2010	Increased apoptosis and decreased proliferation of colonic epithelium in dextran sulfate sodium-induced colitis in mice.
3/2010	Cellobiose Prevents the Development of Dextran Sulfate Sodium (DSS)-Induced Experimental Colitis.
2/2010	Proteus mirabilis sp. intestinal microflora grow in a dextran sulfate sodium-rich environment.
10/2008	FR167653, a p38 mitogen-activated protein kinase inhibitor, aggravates experimental colitis in mice.
1/2008	Lack of macrophage migration inhibitory factor suppresses innate immune response in murine dextran sulfate sodium-induced colitis.
11/2007	Curcumin prevents the development of dextran sulfate Sodium (DSS)-induced experimental colitis.
2/2007	Germinated barley foodstuff suppresses dextran sulfate experimental colitis in rats: the role of mast cells.

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Yoshihide Fujiyama Research Topics

Disease

31	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2013 - 04/2002
26	Ulcerative Colitis 04/2013 - 01/2002
24	Colitis 01/2013 - 01/2002
23	Crohn Disease (Crohn's Disease) 04/2014 - 01/2003
14	Neoplasms (Cancer) 07/2014 - 02/2002
14	Inflammation (Inflammations) 11/2012 - 01/2002
7	Infections 02/2019 - 03/2003
7	Body Weight (Weight, Body) 06/2011 - 04/2002
5	Carcinoma (Carcinomatosis) 07/2013 - 06/2003
5	Pathologic Constriction (Stenosis) 02/2008 - 06/2005
5	Pancreatitis 08/2005 - 01/2002
4	Chronic Pancreatitis 12/2011 - 01/2003
4	Ascites 01/2007 - 04/2002
3	Hepatocellular Carcinoma (Hepatoma) 07/2014 - 07/2011
3	Colorectal Neoplasms (Colorectal Cancer) 02/2014 - 06/2011
3	Ulcer 02/2013 - 10/2003
3	Adenoma (Adenomas) 12/2012 - 01/2008
3	Esophageal Neoplasms (Esophageal Cancer) 06/2012 - 08/2007
3	Gastroesophageal Reflux (GERD) 04/2012 - 01/2002
3	Hemorrhage 06/2008 - 06/2002
3	Esophageal Stenosis (Esophageal Stricture) 02/2008 - 01/2006
3	Animal Diseases 10/2003 - 01/2002
2	Peritonitis 02/2019 - 01/2007
2	Acquired Immunodeficiency Syndrome (AIDS) 02/2019 - 05/2007
2	Carcinogenesis 11/2013 - 08/2004
2	Stomach Neoplasms (Stomach Cancer) 11/2013 - 01/2007
2	Adenocarcinoma 11/2013 - 01/2008
2	Chronic Hepatitis C 01/2012 - 09/2008
2	Hepatitis C 07/2011 - 09/2008
2	Fibrosis (Cirrhosis) 04/2010 - 07/2006
2	Edema (Dropsy) 03/2010 - 11/2007
2	Disease Progression 05/2007 - 06/2002
2	Stroke (Strokes) 07/2003 - 07/2003

Drug/Important Bio-Agent (IBA)

18	Dextran SulfateIBA 01/2013 - 04/2002
14	Therapeutic UsesIBA 11/2012 - 01/2002
9	Proteins (Proteins, Gene)FDA Link 01/2014 - 01/2002
8	CytokinesIBA 09/2013 - 12/2004
7	SteroidsIBA 07/2014 - 12/2008
7	Volatile Fatty AcidsIBA 01/2011 - 01/2002
6	Infliximab (Remicade)FDA Link 04/2014 - 01/2003
6	AntibodiesIBA 01/2014 - 05/2002
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2013 - 07/2002
5	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2013 - 01/2002
5	Dextrans (Dextran)FDA Link 01/2013 - 01/2002
5	InterferonsIBA 01/2012 - 09/2008
5	Messenger RNA (mRNA)IBA 10/2011 - 06/2003
5	PrebioticsIBA 01/2011 - 01/2002
5	Interleukin-6 (Interleukin 6)IBA 11/2004 - 01/2002
4	Complement System Proteins (Complement)IBA 01/2013 - 02/2002
4	InterleukinsIBA 05/2011 - 07/2002
4	Butyrates (Butyrate)IBA 01/2011 - 01/2002
4	Azathioprine (Imuran)FDA LinkGeneric 01/2011 - 01/2008
3	LigandsIBA 02/2014 - 06/2011
3	Polysaccharides (Glycans)IBA 02/2014 - 08/2004
3	MucinsIBA 11/2013 - 03/2009
3	DNA (Deoxyribonucleic Acid)IBA 07/2013 - 06/2003
3	Peroxidase (Myeloperoxidase)IBA 01/2013 - 04/2002
3	Tacrolimus (Prograf)FDA LinkGeneric 11/2012 - 01/2011
3	Cyclosporine (Ciclosporin)FDA LinkGeneric 07/2012 - 03/2010
3	Bile Acids and Salts (Bile Acids)IBA 04/2012 - 11/2002
3	Ribavirin (Virazole)FDA LinkGeneric 01/2012 - 07/2011
3	Interleukin-33IBA 10/2011 - 04/2010
3	2-mercaptopurineIBA 09/2011 - 09/2008
3	Immunosuppressive Agents (Immunosuppressants)IBA 01/2011 - 01/2008
3	Dietary Fiber FDA Link 02/2007 - 01/2003
3	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2003 - 04/2002
3	IS 741IBA 01/2003 - 04/2002
2	Interferon-gamma (Interferon, gamma)IBA 02/2019 - 01/2011
2	Sorafenib (BAY 43-9006)FDA Link 07/2014 - 07/2013
2	LectinsIBA 02/2014 - 10/2003
2	Indicators and Reagents (Reagents)IBA 02/2014 - 12/2012
2	Adalimumab (Humira)FDA Link 01/2014 - 02/2013
2	Tumor Biomarkers (Tumor Markers)IBA 01/2014 - 06/2011
2	Monoclonal AntibodiesIBA 11/2013 - 01/2004
2	Prednisolone (Predate)FDA LinkGeneric 07/2013 - 10/2002
2	Macrophage Migration-Inhibitory FactorsIBA 06/2012 - 01/2008
2	Cell Adhesion MoleculesIBA 06/2011 - 01/2003
2	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 06/2011 - 05/2007
2	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 01/2011 - 09/2008
2	AcidsIBA 01/2011 - 02/2006
2	Phenobarbital (Luminal)FDA Link 01/2011 - 06/2002
2	Immunologic Factors (Immunomodulators)IBA 01/2011 - 05/2007
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 04/2010 - 06/2003
2	poly(lactide) (polylactic acid)IBA 02/2008 - 08/2007
2	Pharmaceutical PreparationsIBA 01/2008 - 01/2007
2	SolutionsIBA 01/2008 - 01/2003
2	CausticsIBA 08/2007 - 01/2006
2	Glutamine (L-Glutamine)FDA Link 11/2003 - 01/2003
2	Dietary Fats (Dietary Fat)IBA 11/2003 - 02/2003
2	Sulfonic AcidsIBA 11/2003 - 01/2003
2	Amylases FDA Link 07/2003 - 04/2002

Therapy/Procedure

32	Therapeutics 07/2014 - 10/2002
8	Oral Administration 01/2011 - 01/2002
4	Stents 06/2012 - 01/2006
2	Drug Therapy (Chemotherapy) 01/2017 - 01/2007
2	Surgical Instruments (Clip) 12/2012 - 08/2004
2	Colectomy 07/2012 - 09/2005
2	Laparotomy 11/2007 - 04/2004
2	Enteral Nutrition (Feeding, Tube) 11/2007 - 01/2003
2	Blood Component Removal (Apheresis) 08/2005 - 04/2005